This research sought to investigate the effect of smart Agri-preneurship dimensions on food affordability in South-West, Nigeria. Diverse literature confirmed positions of scholarly discourse regarding the relationship between smart Agri-preneurship dimensions and food affordability. Cross-sectional research design was adopted while adopted questionnaire was used to source primary data. Duly registered Agri-preneurs in South-West Nigeria were selected with a population of (2,557). Cochran, Hatzes, Butler, and Marcy formula (1997) was adopted and a reliable and valid questionnaire was tested on 558Agri-preneurs. The regressed constructs revealed a positive and significant effect of smart Agri-preneurship on food affordability.